Acids play an important role in human nutrition and health maintenance. Nowadays amino acids are used as animal feed additives, flavor enhancers, ingredients in cosmetic and pharmaceutical products and as specialty nutrients in the medical field, and the production capacity requirements are constantly increasing. Biotechnology methods are widely established in the production of proteinogenic amino acids. Amino acids are routinely manufactured applying biotechnology methods mostly from specially developed mutants of C. glutamic or E. coli.